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Figure 4. Clinical opportunities for fenretinide in cancer. Schematic overview of possible applications of novel fenretinide nanoformulations in the clinical management of cancer patients. Potential uses of the compound at various stages of patient treatment are suggested: as a chemopreventive agent, as part of standard therapeutic regimens intercalated with chemotherapy agents, or for long-term disease control in advanced tumors. Created in BioRender. Verachi, P. (2026) https://BioRender.com/mu883r2.