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Adaptive drug resistance in melanoma is characterised by lipidome remodelling while maintaining cell membrane biophysical properties
Open Access Original Article 16 Sep 2026
DOI:
10.20517/cdr.2026.54
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PSMD14 as a translational target in cancer and beyond: from deubiquitination mechanisms to drug resistance and precision therapy
Open Access Review 7 Sep 2026
DOI:
10.20517/cdr.2026.80
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Resistance to third-generation EGFR TKIs - what can be expected from the fourth-generation?
Open Access Review 3 Sep 2026
DOI:
10.20517/cdr.2026.79
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ST6GAL1 promotes cancer stem-like cell-associated paclitaxel resistance through the EGFR-mTOR-SOX2/BMI1 axis in non-small cell lung cancer
Open Access Original Article 31 Aug 2026
DOI:
10.20517/cdr.2026.66
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Bracing for the storm: emerging resistance mechanisms to KRAS inhibitors in pancreatic cancer and strategies to overcome them
Open Access Review 31 Aug 2026
DOI:
10.20517/cdr.2026.52
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Divergent transcriptional programs and constrained metabolic states reveal selective metabolic dependencies in chemoresistant luminal breast cancer
Open Access Original Article 28 Aug 2026
DOI:
10.20517/cdr.2026.57
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Adenylosuccinate lyase in pancreatic ductal adenocarcinoma chemoresistance: from purine metabolism to metabolic vulnerability
Open Access Review 24 Aug 2026
DOI:
10.20517/cdr.2026.58
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Mitochondrial LINC01133 regulates pyroptosis and calcium homeostasis in cisplatin-resistant lung adenocarcinoma
Open Access Original Article 11 Aug 2026
DOI:
10.20517/cdr.2026.39
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TET2 downregulation limits oxidative stress-induced cytotoxicity of high dose ascorbate in dabrafenib-resistant melanoma cells
Open Access Original Article 3 Aug 2026
DOI:
10.20517/cdr.2026.42
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Mechanistic roles and clinical applications of tertiary lymphoid structures in colorectal cancer drug resistance
Open Access Review 28 Jul 2026
DOI:
10.20517/cdr.2026.35
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An epithelial-mesenchymal transition-related gene signature predicts prognosis, immune infiltration, and drug sensitivity in colorectal cancer
Open Access Original Article 27 Jul 2026
DOI:
10.20517/cdr.2026.37
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Lack of resolution of inflammation marks malignant pleural mesothelioma progression
Open Access Original Article 23 Jul 2026
DOI:
10.20517/cdr.2026.33
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LINC01607 promotes hepatocellular carcinoma progression and ferroptosis-associated therapy resistance with functional involvement of the p62–Keap1–Nrf2 pathway
Open Access Original Article 17 Jul 2026
DOI:
10.20517/cdr.2026.02
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Unveiling the role of UGT enzymes in chemoresistance: a path to enhanced cancer pharmacotherapy
Open Access Original Article 8 Jun 2026
DOI:
10.20517/cdr.2026.10
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A systematic review and network meta analysis of first-line immunotherapy for advanced urothelial carcinoma
Open Access Meta-Analysis 5 Jun 2026
DOI:
10.20517/cdr.2026.22
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Fenretinide in cancer therapy and chemoprevention: past, present and future
Open Access Review 5 Jun 2026
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Deep spatial proteomics reveals a suppressive immune niche linked to immune evasion in renal cell carcinoma
Open Access Original Article 19 May 2026
DOI:
10.20517/cdr.2026.27
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Overcoming resistance to anti-PD-1/PD-L1 therapy in cancer
Open Access Review 15 May 2026
DOI:
10.20517/cdr.2026.12
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