fig4

From: Advances in sudden unexplained death: novel insights into technical innovations and their applications in forensic investigation

Figure 4. Integrated analytical framework for the application of AI in forensic investigation of SUDs. This schematic illustrates the multi-modal strategy combining multi-omics and spectroscopic approaches, virtual autopsy imaging techniques, and AI (ML and DL) for precise COD determination, pathophysiological mechanism interpretation, and evidence-based diagnosis in SUD cases (including SCD, SIDS, and SUDEP). Created in BioRender. qi, M. (2026) https://BioRender.com/oepjqkf. SUD: Sudden unexplained death; NGS: next-generation sequencing; SERS: surface-enhanced Raman spectroscopy; FTIR: Fourier transform infrared; DANN: deleterious annotation of genetic variants using neural networks; CNN: convolutional neural network; SVM: support vector machine; AI: artificial intelligence.