fig8

Figure 8. (A) Preparation process of HFH-COFs@Au@GSH with TEM image; (B) Workflow of N-glycopeptide enrichment using the HFH-COFs@Au@GSH; (C) N-Glycosylation sites identified from human serum; (D) Web-Logos of N-glycosylation sites identified from human serum; GO analysis by DAVID for the identified glycoproteins from human serum, including the cellular component (E), biological process (F), and molecular function (G); (H) Synthetic schematics of TbBD@PEI@Au@4-MPBA composites and Enrichment procedure of glycopeptides by TbBD@PEI@Au@4-MPBA; (I and J) SEM (I) and TEM (J) images of the TbBD@PEI@Au@4-MPBA. (A-G) are reprinted with permission from Ref.^[127], Copyright © 2022 by Royal Society of Chemistry. (H-J) are reproduced with permission from Ref.^[125], Copyright © 2022 by Elsevier. GSH: Glutathione; TEM transmission electron microscopy; GO: Gene Ontology; DAVID: database for annotation, visualization, and integrated discovery; TbBD: 1,1,4,4-tetraphenyl-1,3-butadiene; PEI: polyethyleneimine; MPBA: mercaptophenylboronic acid; SEM: scanning electron microscope.