fig1
Figure 1. Iron metabolism pathways in physiological and α-syn-associated pathological conditions. FPN1: Ferroportin 1; TFR: transferrin receptor; PL-OOH: phospholipid hydroperoxide; PL-OH: phospholipid alcohols; PUFA: polyunsaturated fatty acid; GSH: glutathione; GPX4: glutathione peroxidase 4; GS-SG: glutathione disulfide; ROS: reactive oxygen species; DMT1: divalent metal transporter 1; IRP-IRE: iron regulatory protein-iron responsive element.