fig6

The lnc-MAPKAPK5-AS1 promotes colon cancer-derived liver metastasis via modulating the tumor microenvironment: an <i>in silico</i> study and immunohistochemistry validation

Figure 6. Correlation analysis between MK5-AS1 and immune microenvironment. (A-C) The relationships between MK5-AS1 and ESTIMATE score, Immune score, and Stromal score. (D and E) The proportions of 22 types of immune cells in colon cancer tissues and liver metastasis. (F) Expression patterns of eight immune checkpoint genes between the MK5-AS1 high expression group and the low expression group. (G) The expression characteristics of 22 immune cell phenotypes were calculated based on the “CIBERSORT” algorithm. (H) The expression of 64 types of immune cells extracted based on the “xCell” algorithm was shown in different groups. Statistical significance is indicated as follows: *P < 0.05, **P < 0.01, ***P < 0.001; ns: not significant (P ≥ 0.05).

Journal of Cancer Metastasis and Treatment
ISSN 2454-2857 (Online) 2394-4722 (Print)

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